Drosophila Interspecific Hybridization Causes A Deregulation of the piRNA Pathway Genes.

ABSTRACT: Almost all eukaryotes have transposable elements (TEs) against which they have developed defense mechanisms. In the Drosophila germline, the main transposable element (TE) regulation pathway is mediated by specific Piwi-interacting small RNAs (piRNAs). Nonetheless, for unknown reasons, TEs sometimes escape cellular control during interspecific hybridization processes. Because the piRNA pathway genes are involved in piRNA biogenesis and TE control, we sequenced and characterized nine key genes from this pathway in Drosophilabuzzatii and Drosophilakoepferae species and studied their expression pattern in ovaries of both species and their F1 hybrids. We found that gene structure is, in general, maintained between both species and that two genes-armitage and

SUBMITTER: Gamez-Visairas V 

PROVIDER: S-EPMC7073935 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature