Risk factors for incident heart failure in age- and sex-specific strata: a population-based cohort using linked electronic health records.

ABSTRACT:

Aims

Several risk factors for incident heart failure (HF) have been previously identified, however large electronic health records (EHR) datasets may provide the opportunity to examine the consistency of risk factors across different subgroups from the general population.

Methods and results

We used linked EHR data from 2000 to 2010 as part of the UK-based CALIBER resource to select a cohort of 871 687 individuals 55 years or older and free of HF at baseline. The primary endpoint was the first record of HF from primary or secondary care. Cox proportional hazards analysis was used to estimate hazard ratios for associations between risk factors and incident HF, separately for men and women and by age category: 55-64, 65-74, and > 75 years. During 5.8 years of median follow-up,

SUBMITTER: Uijl A 

PROVIDER: S-EPMC7074015 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature