Surface-Dependent Osteoblasts Response to TiO₂ Nanotubes of Different Crystallinity.

ABSTRACT: One of the major challenges of implantology is to design nanoscale modifications of titanium implant surfaces inducing osseointegration. The aim of this study was to investigate the behavior of rat osteoblasts cultured on anodized TiO₂ nanotubes of different crystallinity (amorphous and anatase phase) up to 24 days. TiO₂ nanotubes were fabricated on VT1-0 titanium foil via a two-step anodization at 20 V using NH₄F as an electrolyte. Anatase-phase samples were prepared by heat treatment at 500 °C for 1 h. VT1-0 samples with flat surfaces were used as controls. Primary rat osteoblasts were seeded over experimental surfaces for several incubation times. Scanning electron microscopy (SEM) was used to analyze tested surfaces and cell morphology. Cell adhesion an

SUBMITTER: Khrunyk YY 

PROVIDER: S-EPMC7075131 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature