Cardiovascular consequences of obstructive sleep apnea in women: a historical cohort study.

ABSTRACT:

Objective/background

Evidence on sex differences in the association between obstructive sleep apnea (OSA) and cardiovascular outcomes is limited and controversial. We conducted a historical cohort study to investigate this relationship.

Patients/methods

Clinical data on adults who underwent sleep study at a large urban academic hospital (Toronto, Canada) between 1994 and 2010 were linked to provincial health administrative data from 1991 to 2015. We fit Cox regressions to investigate the association between OSA severity and a cardiovascular composite outcome (all-cause mortality or hospitalization due to myocardial infarction, stroke, heart failure or atrial fibrillation), controlling for risk factors and stratifying by sex.

Results

A total of 10,149 subjects were inc

SUBMITTER: Kendzerska T 

PROVIDER: S-EPMC7075717 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature