Right-lateralized fronto-parietal network and phasic alertness in healthy aging.

ABSTRACT: Phasic alerting cues temporarily increase the brain's arousal state. In younger and older participants, visual processing speed in a whole report task, estimated based on the theory of visual attention, is higher in cue than no-cue conditions. The present study assessed whether older participants' ability to profit from warning cues is related to intrinsic functional connectivity (iFC) in the cingulo-opercular and/or right fronto-parietal network. We acquired resting-state functional magnetic resonance imaging data from 31 older participants. By combining an independent component analysis and dual regression, we investigated iFC in both networks. A voxel-wise multiple regression in older participants yielded that higher phasic alerting effects on visual processing speed were significantly

SUBMITTER: Haupt M 

PROVIDER: S-EPMC7075959 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature