The prevalence and incidence of vertebral fractures in end-stage renal disease and the role of parathyroid hormone.

ABSTRACT: The risk of vertebral fracture is unclear in end-stage renal disease. We report a high vertebral fracture prevalence and incidence in transplantation-eligible patients on dialysis, suggesting that these patients may benefit from radiographic screening for vertebral fractures. Parathyroid hormone had a U-shaped association with vertebral fracture risk.

Introduction

Vertebral fractures are often overlooked, but even undiagnosed vertebral fractures negatively impact physical functioning, quality of life, and mortality. The risk of vertebral fractures in end-stage renal disease (ESRD) patients is unclear, and parathyroid hormone (PTH) might play a role in the development of vertebral fractures. We therefore determined vertebral fracture prevalence and incidence in ESRD patients and asse

SUBMITTER: Jansz TT 

PROVIDER: S-EPMC7076061 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature