Advances on a Decision Analytic Approach to Exposure-Based Chemical Prioritization.

ABSTRACT: The volume and variety of manufactured chemicals is increasing, although little is known about the risks associated with the frequency and extent of human exposure to most chemicals. The EPA and the recent signing of the Lautenberg Act have both signaled the need for high-throughput methods to characterize and screen chemicals based on exposure potential, such that more comprehensive toxicity research can be informed. Prior work of Mitchell et al. using multicriteria decision analysis tools to prioritize chemicals for further research is enhanced here, resulting in a high-level chemical prioritization tool for risk-based screening. Reliable exposure information is a key gap in currently available engineering analytics to support predictive environmental and health risk assessments. An elic

SUBMITTER: Wood MD 

PROVIDER: S-EPMC7076565 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature