Youth with elevated psychopathic traits exhibit structural integrity deficits in the uncinate fasciculus.

ABSTRACT: Youth with elevated psychopathic traits represent a particularly severe subgroup of adolescents characterized by extreme behavioral problems and exhibit comparable neurocognitive deficits as adult offenders with psychopathic traits. A consistent finding among adults with elevated psychopathic traits is reduced white matter structural integrity of the right uncinate fasciculus (UF). The UF is a major white matter tract that connects regions of the anterior temporal lobe (i.e., the amygdala) to higher-order executive control regions, including the ventromedial prefrontal cortex. However, the relationship between youth psychopathic traits and structural integrity of the UF has been mixed, with some studies identifying a negative relationship between adolescent psychopathy scores and FA in the

SUBMITTER: Maurer JM 

PROVIDER: S-EPMC7076567 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature