Effects of tannase-converted green tea extract on skeletal muscle development.

ABSTRACT: BACKGROUND:The aim of this study was to investigate the effect of tannase-converted green tea extract with a high (-)-epicatechin (EC), (-)-epigallocatechin (EGC), and gallic acid (GA) content on myotube density and fusion in normal and oxidative stress-induced C2C12 skeletal muscle cells. Although the use of green tea extract is considered beneficial, cellular and molecular mechanisms of action of tannase-converted green tea extracts that are used as potential muscle growth materials have not been thoroughly studied. METHODS:This study used histological analysis and molecular biology techniques, and compared the results with those for AMPK activator 5-aminoimidazole-4-carboxamide-1-β-D-ribonucleoside (AICAR) and green tea extracts. RESULTS:The myotube density of normal and oxidative stres

SUBMITTER: Hong KB 

PROVIDER: S-EPMC7076851 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature