Antibacterial activity of Centaurea pumilio L. root and aerial part extracts against some multidrug resistant bacteria.

ABSTRACT: BACKGROUND:In the context of searching for potent, safe, natural antimicrobial agents to combate the global antimicrobial resistance (AMR) phenomenon, the current study evaluates for the first time ever, the broad-spectrum antimicrobial activity of essential oil (EO) and extracts from the rare wild plant Centaurea pumilio L.. It has tremendous ethnomedicinal values; its dried root is used as a fattening agent, a treatment for bad breath and diabetes, and screened for schistosomicidal activity. METHODS:C. pumilio EO was extracted by hydrodistillation using a Clevenger apparatus. Chemical constituents of aerial part were extracted using a sequential solvent/solvent procedure employing four solvents with increasing polarities in the following order: petroleum ether, chloroform, ethyl acetate,

SUBMITTER: Naeim H 

PROVIDER: S-EPMC7076891 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature