Endotoxin clustering with allergens in house dust and asthma outcomes in a U.S. national study.

ABSTRACT:

Background

Endotoxin is ubiquitous in the environment, but its clustering with indoor allergens is not well characterized. This study examined the clustering patterns of endotoxin with allergens in house dust and their association with asthma outcomes.

Methods

We analyzed data from 6963 participants of the 2005-2006 National Health and Nutrition Examination Survey. House dust sampled from bedroom floor and bedding was evaluated for endotoxin and allergens from fungi, cockroach, dog, cat, mites, and rodents. Two-step cluster analysis and logistic regressions were performed to identify the clustering patterns and their associations with current asthma and wheeze in the past 12 months, adjusting for covariates.

Results

Of the homes, 17.8% had low endotoxin and allergen l

SUBMITTER: Mendy A 

PROVIDER: S-EPMC7077112 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature