The Detection and Association of Canine Papillomavirus with Benign and Malignant Skin Lesions in Dogs.

ABSTRACT: Papillomavirus (PV) mainly infects the squamous epithelium and may potentially lead to benign or even malignant cutaneous lesions. However, the malignant transforming ability has been identified in several types of PVs. In humans, papillomavirus (HPV) type 16 and 18 are the most prevalent causative agents of cervical cancer. Therefore, vaccines are being developed to protect against these types. For dogs, there have been limited investigations into the association of different canine papillomavirus (CPV) genotypes with malignant lesions. Understanding the high-risk CPV genotype(s) responsible for these malignant lesions would contribute to the development of interventions for preventing CPV-induced carcinomas. In the present study, a retrospective cohort of 102 pathologically confirmed pap

SUBMITTER: Chang CY 

PROVIDER: S-EPMC7077320 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature