Synthesis, Characterization, Self-Assembly, and Irritation Studies of Polyglyceryl-10 Caprylates.

ABSTRACT: 1,4-dioxane should be less than or equal to 10 ppm in finished cosmetic products according to the recommendation of the Scientific Committee on Consumer Safety, but it is often generated as a by-product during the manufacturing process of poly(ethylene glycol) (PEG)-based derivatives. In order to avoid the possible risk caused by 1,4-dioxane, it might be a good choice for preparing cosmetic ingredients by using polyglycerin (PG) instead of PEG as a hydrophilic segment. In the present study, polyglyceryl-10 caprylates were synthesized by the esterification reaction between polyglycerin-10 and caprylic acid. FTIR and 1H NMR were utilized to confirm the chemical structures of the obtained polyglyceryl-10 caprylates. Light transmittance was availed to investigate the water solubility of polygl

SUBMITTER: Zhang G 

PROVIDER: S-EPMC7077386 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature