Neural substrates of smoking and reward cue reactivity in smokers: a meta-analysis of fMRI studies.

ABSTRACT: Smoking is partly attributed to alterations of reward processing. However, findings on the neurobiological mechanisms that underlie smoking-related and smoking-unrelated reward processing in smokers have been inconsistent. Neuroimaging experiments that used functional magnetic resonance imaging (fMRI) and reported brain responses to smoking-related cues and nonsmoking reward-related cues in smokers and healthy controls as coordinates in a standard anatomic reference space were identified by searching the PubMed, Embase, and Web of Science databases up to December 2018. Three meta-analyses were performed using random-effect nonparametric statistics with Seed-based d Mapping software, with brain activity contrast from individual studies as the input. The striatum showed higher activation in

SUBMITTER: Lin X 

PROVIDER: S-EPMC7078287 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature