Association of PROtein and CAloric Intake and Clinical Outcomes in Adult SEPTic and Non-Septic ICU Patients on Prolonged Mechanical Ventilation: The PROCASEPT Retrospective Study.

ABSTRACT:

Background

The optimal nutritional support for critically ill septic patients remains unknown. This study evaluates the associations of macronutrient intake during the first week of intensive care unit (ICU) admission and long-term clinical outcomes in septic and non-septic patients.

Methods

Prolonged mechanically ventilated patients were retrospectively studied. The association of protein (low: <0.8 g/kg/d, medium: 0.8-1.2 g/kg/d, high >1.2 g/kg/d) and energy intake (<80%, 80%-110%, 110% of target) during days 1-3 and 4-7 after ICU admission and 6-month mortality was analyzed for septic and non-septic patients separately.

Results

A total of 423 patients were investigated. Of these, 297 had sepsis. In the sepsis group, medium protein intake at days 4-7 was associated

SUBMITTER: de Koning MLY 

PROVIDER: S-EPMC7078979 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature