Maternal characteristics and causes associated with refractory postpartum haemorrhage after vaginal birth: a secondary analysis of the WHO CHAMPION trial data.

ABSTRACT:

Objective

To assess the maternal characteristics and causes associated with refractory postpartum haemorrhage (PPH).

Design

Secondary analysis of the WHO CHAMPION trial data.

Setting

Twenty-three hospitals in ten countries.

Population

Women from the CHAMPION trial who received uterotonics as first-line treatment of PPH.

Methods

We assessed the association between sociodemographic, pregnancy and childbirth factors and refractory PPH, and compared the causes of PPH between women with refractory PPH and women responsive to first-line PPH treatment.

Main outcome measures

Maternal characteristics; causes of PPH.

Results

Women with labour induced or augmented with uterotonics (adjusted odds ratio [aOR] 1.35; 95% CI 1.07-1.72), with episiotomy or

SUBMITTER: Widmer M 

PROVIDER: S-EPMC7078998 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature