Exercise-Induced Neuroplasticity in Parkinson's Disease: A Metasynthesis of the Literature.

ABSTRACT: Parkinson's disease (PD) is a neurodegenerative disorder for which there is currently only symptomatic treatment. During the last decade, there has been an increased interest in investigating physical exercise as a neuroprotective mechanism in PD. Animal studies have suggested that exercise may in fact induce neuroplastic changes, but evidence in humans is still scarce. A handful of reviews have previously reported on exercise-induced neuroplasticity in humans with PD, but few have been systematic, or have mixed studies on both animals and humans, or focused on one neuroplastic outcome only. Here, we provide a systematic review and metasynthesis of the published studies on humans in this research field where we have also included different methods of evaluating neuroplasticity. Our results

SUBMITTER: Johansson H 

PROVIDER: S-EPMC7079218 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature