Serum IgG Antibodies against Periodontal Microbes and Cancer Mortality.

ABSTRACT:

Introduction

Periodontitis is a chronic inflammatory condition initiated by microorganisms and is positively linked to systemic conditions such as cancer, cardiovascular disease, and diabetes mellitus.

Objectives

To prospectively investigate associations between empirically derived clusters of IgG antibodies against 19 selected periodontal microorganisms and cancer mortality in a representative sample of the US population.

Methods

We evaluated 6,491 participants aged ≥40 y from the Third National Health and Nutrition Examination Survey (1988 to 1994), who had complete data on IgG antibody titers against 19 selected periodontal microorganisms and were free of cardiovascular disease and cancer. In a prior study, antibodies were categorized into 4 mutually exclusive grou

SUBMITTER: Zhong Z 

PROVIDER: S-EPMC7079332 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature