RASflow: an RNA-Seq analysis workflow with Snakemake.

ABSTRACT:

Background

With the cost of DNA sequencing decreasing, increasing amounts of RNA-Seq data are being generated giving novel insight into gene expression and regulation. Prior to analysis of gene expression, the RNA-Seq data has to be processed through a number of steps resulting in a quantification of expression of each gene/transcript in each of the analyzed samples. A number of workflows are available to help researchers perform these steps on their own data, or on public data to take advantage of novel software or reference data in data re-analysis. However, many of the existing workflows are limited to specific types of studies. We therefore aimed to develop a maximally general workflow, applicable to a wide range of data and analysis approaches and at the same time support rese

SUBMITTER: Zhang X 

PROVIDER: S-EPMC7079470 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature