Long-term follow-up, quality of life, and survival of patients with Lambert-Eaton myasthenic syndrome.

ABSTRACT:

Objective

To study survival and to characterize long-term functional impairments and health-related quality of life (HRQOL) of patients with Lambert-Eaton myasthenic syndrome (LEMS).

Methods

In this observational study, survival of patients with LEMS, separately for nontumor (NT) and small cell lung cancer (SCLC), was compared to that of the Dutch general population and patients with SCLC. Disease course in patients with LEMS was recorded retrospectively. Several scales for functional impairments and health-related quality of life were assessed.

Results

We included 150 patients with LEMS. Survival was similar to that of the general population in 65 patients with NT-LEMS. Tumor survival was significantly longer in 81 patients with SCLC-LEMS compared to patients with no

SUBMITTER: Lipka AF 

PROVIDER: S-EPMC7080283 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature