The response of a standardized fluid challenge during cardiac surgery on cerebral oxygen saturation measured with near-infrared spectroscopy.

ABSTRACT: Near infrared spectroscopy (NIRS) has been used to evaluate regional cerebral tissue oxygen saturation (ScO₂) during the last decades. Perioperative management algorithms advocate to maintain ScO₂, by maintaining or increasing cardiac output (CO), e.g. with fluid infusion. We hypothesized that ScO₂ would increase in responders to a standardized fluid challenge (FC) and that the relative changes in CO and ScO₂ would correlate. This study is a retrospective substudy of the FLuid Responsiveness Prediction Using Extra Systoles (FLEX) trial. In the FLEX trial, patients were administered two standardized FCs (5 mL/kg ideal body weight each) during cardiac surgery. NIRS monitoring was used during the intraoperative period and CO was monitored continuous

SUBMITTER: Holmgaard F 

PROVIDER: S-EPMC7080680 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature