Evaluation of ten SNP Markers for Human Identification and Paternity Analysis in Persian Population.

ABSTRACT:

Background

DNA markers are inevitable tools of human identification in forensic science. Single Nucleotide Polymorphisms (SNPs) are one category of these markers which is concerned to use especially in the case of degraded DNA because of their short amplicons.

Objectives

Detection of highly informative SNPs by the criteria is the essential step to develop a useful panel of SNP markers. The purpose of this work is to get high informative SNPs for human identification in Persian ethnic of the Iranian population.

Material and methods

Genotype and allele frequencies of 10 SNPs from the SNPforID browser were determined by a PCR-RFLP method on 100 samples that was taken from 100 unrelated Persian people.

Results

These ten SNPs were in Hardy-Weinberg equilibrium (P

SUBMITTER: Habibi S 

PROVIDER: S-EPMC7080969 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature