Multicap to improve adherence after acute coronary syndromes: results of a randomized controlled clinical trial.

ABSTRACT:

Background

Adherence to treatment after a myocardial infarction (MI) is poor, even in the early postinfarction period. Combining evidence-based drugs into a multicap could improve adherence in this population. No previous randomized trial assessing fixed-dose combination therapy has included patients early after a MI. We aimed to assess if a multicap containing four secondary prevention drugs increases adherence to treatment at 6 months after MI hospitalization. The study was designed as a randomized, parallel, open-label, controlled trial.

Methods

Patients were randomized within 7 days of a MI to either multicap or control group. The multicap group received a capsule containing aspirin, atenolol, ramipril, and simvastatin. The control group received each drug in separate pi

SUBMITTER: Mariani J 

PROVIDER: S-EPMC7081461 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature