Efficacy and safety of thromboprophylaxis in cancer patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Thrombosis is a common complication in patients with cancer. Whether thromboprophylaxis could benefit patients with cancer is unclear. The aim of this systematic review was to determine the efficacy and safety of thromboprophylaxis in patients with cancer undergoing surgery or chemotherapy.

Methods

We searched the Cochrane Library, EMBASE, MEDLINE, EBSCOhost, and Web of Science for studies published before May 2018 to investigate whether thromboprophylaxis measures were more effective than a placebo in patients with cancer.

Results

In total, 33 trials with 11,942 patients with cancer were identified. In patients with cancer undergoing surgery, the administration of thromboprophylaxis was associated with decreasing trends in venous thromboembolism (VTE) [rel

SUBMITTER: Liu M 

PROVIDER: S-EPMC7081475 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature