Neuron ID dataset facilitates neuronal annotation for whole-brain activity imaging of C. elegans.

ABSTRACT:

Background

Annotation of cell identity is an essential process in neuroscience that allows comparison of cells, including that of neural activities across different animals. In Caenorhabditis elegans, although unique identities have been assigned to all neurons, the number of annotatable neurons in an intact animal has been limited due to the lack of quantitative information on the location and identity of neurons.

Results

Here, we present a dataset that facilitates the annotation of neuronal identities, and demonstrate its application in a comprehensive analysis of whole-brain imaging. We systematically identified neurons in the head region of 311 adult worms using 35 cell-specific promoters and created a dataset of the expression patterns and the positions of the neurons.

SUBMITTER: Toyoshima Y 

PROVIDER: S-EPMC7081613 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature