Development and Validation of the TRansparent Uncertainty ASsessmenT (TRUST) Tool for Assessing Uncertainties in Health Economic Decision Models.

ABSTRACT:

Background

An increasing number of technologies are obtaining marketing authorisation based on sparse evidence, which causes growing uncertainty and risk within health technology reimbursement decision making. To ensure that uncertainty is considered and addressed within health technology assessment (HTA) recommendations, uncertainties need to be identified, included in health economic models, and reported.

Objective

Our objective was to develop the TRansparent Uncertainty ASsessmenT (TRUST) tool for systematically identifying, assessing, and reporting uncertainties in decision models, with the aim of making uncertainties and their impact on cost effectiveness more explicit and transparent.

Methods

TRUST was developed by drawing on the uncertainty and risk assessment

SUBMITTER: Grimm SE 

PROVIDER: S-EPMC7081657 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature