Stereotactic body radiotherapy versus percutaneous local tumor ablation for early-stage non-small cell lung cancer.

ABSTRACT:

Objectives

To compare patterns of care and overall survival (OS) between stereotactic body radiotherapy (SBRT) and percutaneous local tumor ablation (LTA) for non-surgically managed early-stage non-small-cell lung cancer (NSCLC).

Materials and methods

The National Cancer Database (NCDB) was queried from 2004 to 2014 for adults with non-metastatic, node-negative invasive adenocarcinoma or squamous cell carcinoma of the lung with primary tumor size ≤5.0 cm who did not undergo surgery or chemotherapy and received SBRT or LTA. Patterns of care were assessed with multivariate logistic regression. After propensity-score weighting with generalized boosted regression, OS was assessed with univariate and doubly-robust multivariate Cox regression.

Results

Of 15,792 patients, 14

SUBMITTER: Ager BJ 

PROVIDER: S-EPMC7082035 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature