Low-dose CT lung cancer screening in never-smokers and smokers: results of an eight-year observational study.

ABSTRACT:

Background

This was an observational study of Japanese participants who underwent low-dose computed tomographic (LDCT) lung cancer screening between February 2004 and March 2012, to evaluate the lung cancers in never-smokers and smokers.

Methods

The study population consisted of a total of 12,114 subjects [never-smokers, 6,021 (49.70%); smokers with <30 pack-years of smoking, 3,785 (31.24%); smokers with ≥30 pack-years of smoking, 2,305 (19.03%); unknown smoking status, 3 (0.02%)]. The odds ratio (OR) of lung cancer detection according to the smoking status adjusted for age and gender was evaluated.

Results

A total of 152 lung cancers were diagnosed in 133 patients [never-smokers, 66 (49.6%); smokers with <30 pack-years of smoking, 31 (23.3%); smokers with ≥30 pack-ye

SUBMITTER: Kakinuma R 

PROVIDER: S-EPMC7082286 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature