Role of Cecal Microbiota in the Differential Resistance of Inbred Chicken Lines to Colonization by <i>Campylobacter jejuni</i>.

ABSTRACT: Campylobacteriosis is the leading foodborne bacterial diarrheal illness in many countries, with up to 80% of human cases attributed to the avian reservoir. The only control strategies currently available are stringent on-farm biosecurity and carcass treatments. Heritable differences in the resistance of chicken lines to Campylobacter colonization have been reported and resistance-associated quantitative trait loci are emerging, although their impact on colonization appears modest. Recent studies indicated a protective role of the microbiota against colonization by Campylobacter in chickens. Furthermore, in murine models, differences in resistance to bacterial infections can be partially transferred between lines by transplantation of gut microbiota. In this study, we investig

SUBMITTER: Chintoan-Uta C 

PROVIDER: S-EPMC7082564 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature