Incidence and Progression of Nongeographic Atrophy in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Clinical Trial.

ABSTRACT:

Importance

Retinal hypopigmentation and hyperpigmentation are precursors of geographic atrophy (GA). Incidence and progression to GA in eyes treated with anti-vascular endothelial growth factor for neovascular age-related macular degeneration (nAMD) have not been investigated.

Objective

To determine the incidence and progression of non-GA (NGA) and associated risk factors.

Design, setting, and participants

This study is a post hoc analysis of a cohort study within the Comparison of Age-Related Treatments Trials (CATT) clinical trial. Participants were recruited February 20, 2008, through December 9, 2009; released from protocol follow-up and treatment after 2 years; and recalled from March 14, 2014, through March 31, 2015. Data analyses were conducted from January 11,

SUBMITTER: Daniel E 

PROVIDER: S-EPMC7082767 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature