A consensus-based framework for conducting and reporting osteoarthritis phenotype research.

ABSTRACT:

Background

The concept of osteoarthritis (OA) heterogeneity is evolving and gaining renewed interest. According to this concept, distinct subtypes of OA need to be defined that will likely require recognition in research design and different approaches to clinical management. Although seemingly plausible, a wide range of views exist on how best to operationalize this concept. The current project aimed to provide consensus-based definitions and recommendations that together create a framework for conducting and reporting OA phenotype research.

Methods

A panel of 25 members with expertise in OA phenotype research was composed. First, panel members participated in an online Delphi exercise to provide a number of basic definitions and statements relating to OA phenotypes and OA

SUBMITTER: van Spil WE 

PROVIDER: S-EPMC7083005 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature