Reduced expression of circRNA hsa_circ_0067582 in human gastric cancer and its potential diagnostic values.

ABSTRACT:

Background

Gastric cancer (GC) is one of the global mortality diseases and has a poor prognosis due to the lack of ideal tumor biomarkers. Circular RNAs (circRNAs) are an abundant kind of endogenous RNAs that recently are found play a crucial role in the cancer occurrence and development. Nevertheless, little is known with regard to the diagnostic values of these circRNAs for GC. In this article of research, we investigated the role of hsa_circ_0067582 in clinical diagnosis of GC.

Materials and methods

We used divergent primers, and the expression levels of hsa_circ_0067582 in 93 fresh GC tissues and paired adjacent normal tissues from surgical patients were detected using quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Then, a receiver operating char

SUBMITTER: Yu X 

PROVIDER: S-EPMC7083425 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature