Systolic blood pressure, heart rate, and outcomes in patients with coronary disease and heart failure.

ABSTRACT:

Aims

Data regarding the optimal systolic blood pressure (SBP) and heart rate (HR) for coronary artery disease (CAD) patients with hypertension and a history of heart failure (HF) are limited. Accordingly, using data from a large clinical trial, we investigated the association between SBP and heart rate and subsequent adverse outcomes in CAD patients with a history of HF, and we aimed to better understand how pre-existing HF impacts outcomes among patients with CAD.

Methods and results

Among 22 576 CAD patients enrolled in the INternational VErapamil SR-Trandolapril STudy (INVEST), 1256 were identified with a history of physician-diagnosed HF New York Heart Association (NYHA) Class 1-3 at entry. The primary outcome was the first occurrence of all-cause death, myocardial infar

SUBMITTER: Elgendy IY 

PROVIDER: S-EPMC7083485 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature