Isolated low levels of high-density lipoprotein cholesterol and stroke incidence: JMS Cohort Study.

ABSTRACT:

Background

The cardiovascular relevance of isolated low levels of high-density lipoprotein cholesterol (HDL-C) is yet to be determined. Stroke often leads to long-term disability, and thus, not only stroke mortality but also stroke incidence is a topic of research. Although isolated low HDL-C level has been found to be a predictor for stroke mortality previously, whether it can predict stroke incidence is unknown.

Methods

In the Jichi Medical School cohort study, 11 025 community-living residents without a history of stroke were examined. Hazard ratios (HRs) for isolated and non-isolated low HDL-C levels were calculated relative to those for normal HDL-C levels in stroke patients using Cox's regression models.

Results

During the mean follow-up period of 10.7 years, 41

SUBMITTER: Watanabe J 

PROVIDER: S-EPMC7083490 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature