Magnetization transfer in magnetic resonance fingerprinting.

ABSTRACT:

Purpose

To study the effects of magnetization transfer (MT, in which a semi-solid spin pool interacts with the free pool), in the context of magnetic resonance fingerprinting (MRF).

Methods

Simulations and phantom experiments were performed to study the impact of MT on the MRF signal and its potential influence on T₁ and T₂ estimation. Subsequently, an MRF sequence implementing off-resonance MT pulses and a dictionary with an MT dimension, generated by incorporating a two-pool model, were used to estimate the fractional pool size in addition to the B1+ , T₁ , and T₂ values. The proposed method was evaluated in the human brain.

Results

Simulations and phantom experiments showed that an MRF signal obtained from a cross-linked

SUBMITTER: Hilbert T 

PROVIDER: S-EPMC7083689 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature