Improved reconstruction stability for chemical shift encoded hyperpolarized ¹³ C magnetic resonance spectroscopic imaging using k-t spiral acquisitions.

ABSTRACT:

Purpose

A multiecho, field of view (FOV)-oversampled k-t spiral acquisition and direct iterative decomposition of water and fat with echo asymmetry and least-squares estimation reconstruction is demonstrated to improve the stability of hyperpolarized ¹³ C magnetic resonance spectroscopic imaging (MRSI) in the presence of signal ambiguities attributed to low-SNR (signal-to-noise-ratio) species, local uncertainties in metabolite peaks, and echo-to-echo signal inconsistencies.

Theory

k-t spiral acquisitions redistribute readout points to be more densely spaced radially in k-space by acquiring an FOV and matrix that are oversampled by η. These more densely spaced spiral turns constitute effective intraspiral echoes and can supplement conventional interspiral echoes to

SUBMITTER: Macdonald EB 

PROVIDER: S-EPMC7083691 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature