Neural correlates of auditory sensory memory dynamics in the aging brain.

ABSTRACT: The auditory system allows us to monitor background environmental sound patterns and recognize deviations that may indicate opportunities or threats. The mismatch negativity and P3a potentials have generators in the auditory and inferior frontal cortex and index expected sound patterns (standards) and any aberrations (deviants). The mismatch negativity and P3a waveforms show increased positivity for consecutive standards and deviants preceded by more standards. We hypothesized attenuated repetition effects in older participants, potentially because of differences in prefrontal functions. Young (23 ± 5 years) and older (75 ± 5 years) adults were tested in 2 oddball paradigms with pitch or location deviants. Significant repetition effects were observed in the young standard and deviant wavef

SUBMITTER: Sur S 

PROVIDER: S-EPMC7085426 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature