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ABSTRACT: Objective
Diabetes is a rapidly growing health problem in low- and middle-income countries (LMICs), but empirical data on its prevalence and relationship to socioeconomic status are scarce. We estimated diabetes prevalence and the subset with undiagnosed diabetes in 29 LMICs and evaluated the relationship of education, household wealth, and BMI with diabetes risk.Research design and methods
We pooled individual-level data from 29 nationally representative surveys conducted between 2008 and 2016, totaling 588,574 participants aged ≥25 years. Diabetes prevalence and the subset with undiagnosed diabetes was calculated overall and by country, World Bank income group (WBIG), and geographic region. Multivariable Poisson regression models were used to estimate relative risk (RR).Results
Overall, prevalence of diabetes in 29 LMICs was 7.5% (95% CI 7.1-8.0) and of undiagnosed diabetes 4.9% (4.6-5.3). Diabetes prevalence increased with increasing WBIG: countries with low-income economies (LICs) 6.7% (5.5-8.1), lower-middle-income economies (LMIs) 7.1% (6.6-7.6), and upper-middle-income economies (UMIs) 8.2% (7.5-9.0). Compared with no formal education, greater educational attainment was associated with an increased risk of diabetes across WBIGs, after adjusting for BMI (LICs RR 1.47 [95% CI 1.22-1.78], LMIs 1.14 [1.06-1.23], and UMIs 1.28 [1.02-1.61]).Conclusions
Among 29 LMICs, diabetes prevalence was substantial and increased with increasing WBIG. In contrast to the association seen in high-income countries, diabetes risk was highest among those with greater educational attainment, independent of BMI. LMICs included in this analysis may be at an advanced stage in the nutrition transition but with no reversal in the socioeconomic gradient of diabetes risk.
SUBMITTER: Seiglie JA
PROVIDER: S-EPMC7085810 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Seiglie Jacqueline A JA Marcus Maja-Emilia ME Ebert Cara C Prodromidis Nikolaos N Geldsetzer Pascal P Theilmann Michaela M Agoudavi Kokou K Andall-Brereton Glennis G Aryal Krishna K KK Bicaba Brice Wilfried BW Bovet Pascal P Brian Garry G Dorobantu Maria M Gathecha Gladwell G Gurung Mongal Singh MS Guwatudde David D Msaidié Mohamed M Houehanou Corine C Houinato Dismand D Jorgensen Jutta Mari Adelin JMA Kagaruki Gibson B GB Karki Khem B KB Labadarios Demetre D Martins Joao S JS Mayige Mary T MT Wong-McClure Roy R Mwangi Joseph Kibachio JK Mwalim Omar O Norov Bolormaa B Quesnel-Crooks Sarah S Silver Bahendeka K BK Sturua Lela L Tsabedze Lindiwe L Wesseh Chea Stanford CS Stokes Andrew A Atun Rifat R Davies Justine I JI Vollmer Sebastian S Bärnighausen Till W TW Jaacks Lindsay M LM Meigs James B JB Wexler Deborah J DJ Manne-Goehler Jennifer J
Diabetes care 20200212 4
<h4>Objective</h4>Diabetes is a rapidly growing health problem in low- and middle-income countries (LMICs), but empirical data on its prevalence and relationship to socioeconomic status are scarce. We estimated diabetes prevalence and the subset with undiagnosed diabetes in 29 LMICs and evaluated the relationship of education, household wealth, and BMI with diabetes risk.<h4>Research design and methods</h4>We pooled individual-level data from 29 nationally representative surveys conducted betwee ...[more]