Dataset Information

Hematocrit and incidence of venous thromboembolism.

ABSTRACT:

Background

Patients with polycythemia vera with high hematocrit have increased risk of venous thromboembolism (VTE).

Objective

To determine whether high hematocrit in the general population is also associated with elevated VTE risk.

Methods

The prospective Atherosclerosis Risk in Communities Study performed a complete blood count in 13 891 adults aged 45 to 64 in 1987 to 1989. We identified incident hospitalized VTEs through 2015 and performed proportional hazards regression analyses using race-sex-specific categorization of hematocrit percentiles (ie, <5th, 5th to <25th, 25th to <75th, 75th to <95th, and 95th-100th percentiles, with the 25th to <75th percentile serving as the reference).