Salmonella Typhimurium infection disrupts but continuous feeding of Bacillus based probiotic restores gut microbiota in infected hens.

ABSTRACT:

Background

The gut microbiota plays an important role in the colonisation resistance and invasion of pathogens. Salmonella Typhimurium has the potential to establish a niche by displacing the microbiota in the chicken gut causing continuous faecal shedding that can result in contaminated eggs or egg products. In the current study, we investigated the dynamics of gut microbiota in laying chickens during Salmonella Typhimurium infection. The optimisation of the use of an infeed probiotic supplement for restoration of gut microbial balance and reduction of Salmonella Typhimurium load was also investigated.

Results

Salmonella infection caused dysbiosis by decreasing (FDR < 0.05) the abundance of microbial genera, such as Blautia, Enorma,

SUBMITTER: Khan S 

PROVIDER: S-EPMC7087389 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature