Longitudinal Changes in Regional Cerebral Perfusion and Cognition After Cardiac Operation.

ABSTRACT:

Background

Cardiac operation has been associated with increased risk of postoperative cognitive decline, as well as dementia risk in the general population. Few studies, however, have examined the impact of coronary revascularization or valve replacement or repair operation on longitudinal cerebral perfusion changes or their association with cognitive function.

Methods

We examined longitudinal changes in cerebral perfusion among 54 individuals with cardiac disease; 27 undergoing cardiac operation and 27 matched control patients. Arterial spin labeling magnetic resonance perfusion imaging was used to quantify cerebral blood flow within the anterior communicating artery, middle cerebral artery (MCA), and posterior communicating artery vascular territories before operation and

SUBMITTER: Smith PJ 

PROVIDER: S-EPMC7087447 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature