Androgenicity and fertility treatment in women with unexplained infertility.

ABSTRACT:

Objective

To determine whether biochemical or clinical markers of androgenic activity predict live birth rate with ovarian stimulation in the unexplained infertility population.

Design

Secondary analysis of the Assessment of Multiple Intrauterine Gestations from Ovarian Stimulation (AMIGOS) clinical trial.

Setting

Multicenter university-based clinical practices.

Patient(s)

Nine hundred couples with unexplained infertility were included. Women were 18-40 years old with regular menses, a normal uterine cavity, at least one patent fallopian tube, and a male partner with ≥5 million motile sperm. Women were randomized to receive gonadotropin, clomiphene, or letrozole with IUI for four or fewer four treatment cycles. Women were evaluated for biochemical (total testos

SUBMITTER: Wang ET 

PROVIDER: S-EPMC7088440 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature