Variability in donor organ offer acceptance and lung transplantation survival.

ABSTRACT:

Background

Lung transplantation offers a survival benefit for patients with end-stage lung disease. When suitable donors are identified, centers must accept or decline the offer for a matched candidate on their waitlist. The degree to which variability in per-center offer acceptance practices impacts candidate survival is not established. The purpose of this study was to determine the degree of variability in per-center rates of lung transplantation offer acceptance and to ascertain the associated contribution to observed differences in per-center waitlist mortality.

Methods

We performed a retrospective cohort study of candidates waitlisted for lung transplantation in the US using registry data. Logistic regression was fit to assess the relationship of offer acceptance with

SUBMITTER: Mulvihill MS 

PROVIDER: S-EPMC7089807 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature