Expression Profile Analysis of the Cell Cycle in Diploid and Tetraploid Carassius auratus red var.
Ontology highlight
ABSTRACT: Polyploidization often leads to "transcriptome shock," and is considered an important factor in evolution of species. Analysis of the cell cycle, which is associated with survival in polyploidy, has proved useful in investigating polyploidization. Here, we used mRNA sequencing to investigate global expression in vitro (in cultured cells) and in vivo (in fin and liver tissues) in both the diploid and tetraploid Carassius auratus red var.. Differential expression (DE) of genes in diploid (7482, 36.0%) and tetraploid (3787, 18.2%) states suggested that in vitro and in vivo conditions dramatically change mRNA expression levels. However, of the 20,771 total shared expressed genes, 18,050 (87.0%), including 17,905 (86.2%) non-differentially expressed genes (DEGs) and 145 (0.7%) DEGs between dipl
SUBMITTER: Ren L
PROVIDER: S-EPMC7089929 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
ACCESS DATA