Prediction of dementia risk in low-income and middle-income countries (the 10/66 Study): an independent external validation of existing models.

ABSTRACT:

Background

To date, dementia prediction models have been exclusively developed and tested in high-income countries (HICs). However, most people with dementia live in low-income and middle-income countries (LMICs), where dementia risk prediction research is almost non-existent and the ability of current models to predict dementia is unknown. This study investigated whether dementia prediction models developed in HICs are applicable to LMICs.

Methods

Data were from the 10/66 Study. Individuals aged 65 years or older and without dementia at baseline were selected from China, Cuba, the Dominican Republic, Mexico, Peru, Puerto Rico, and Venezuela. Dementia incidence was assessed over 3-5 years, with diagnosis according to the 10/66 Study diagnostic algorithm. Discrimination and c

SUBMITTER: Stephan BCM 

PROVIDER: S-EPMC7090906 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature