Thrombolytic therapy in older acute ischemic stroke patients with gastrointestinal malignancy or recent bleeding.

ABSTRACT:

Background

There are limited data on the safety of intravenous recombinant tissue plasminogen activator (rtPA) for treating acute ischemic stroke in patients with gastrointestinal malignancy or recent gastrointestinal bleeding within 21 days of their index stroke.

Aims

To evaluate clinical outcomes in patients treated with rtPA for acute ischemic stroke who had gastrointestinal malignancy or recent gastrointestinal bleeding.

Methods

We identified patients who were treated with rtPA for acute ischemic stroke between 2/2009 and 12/2015 from the Get With The Guidelines-Stroke linked to Medicare claims data. Gastrointestinal malignancy and recent gastrointestinal bleeding were defined as any gastrointestinal malignancy hospitalisation within one year prior to acute ischem

SUBMITTER: Inohara T 

PROVIDER: S-EPMC7092738 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature