Systematic review of reporting benefits and harms of surgical interventions in randomized clinical trials.

ABSTRACT:

Background

Standardized reporting methods facilitate comparisons between studies. Reporting of data on benefits and harms of treatments in surgical RCTs should support clinical decision-making. Correct and complete reporting of the outcomes of clinical trials is mandatory to appreciate available evidence and to inform patients properly before asking informed consent.

Methods

RCTs published between January 2005 and January 2017 in 15 leading journals comparing a surgical treatment with any other treatment were reviewed systematically. The CONSORT checklist, including the extension for harms, was used to appraise the publications. Beneficial and harmful treatment outcomes, their definitions and their precision measures were extracted.

Results

Of 1200 RCTs screened, 88 t

SUBMITTER: Stubenrouch FE 

PROVIDER: S-EPMC7093777 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature