Traveler, a New DD35E Family of Tc1/Mariner Transposons, Invaded Vertebrates Very Recently.

ABSTRACT: The discovery of new members of the Tc1/mariner superfamily of transposons is expected based on the increasing availability of genome sequencing data. Here, we identified a new DD35E family termed Traveler (TR). Phylogenetic analyses of its DDE domain and full-length transposase showed that, although TR formed a monophyletic clade, it exhibited the highest sequence identity and closest phylogenetic relationship with DD34E/Tc1. This family displayed a very restricted taxonomic distribution in the animal kingdom and was only detected in ray-finned fish, anura, and squamata, including 91 vertebrate species. The structural organization of TRs was highly conserved across different classes of animals. Most intact TR transposons had a length of ∼1.5 kb (range 1,072-2,191 bp) and harbored a single

SUBMITTER: Zong W 

PROVIDER: S-EPMC7093834 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature