Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding.

ABSTRACT: We report epidemiological and clinical investigations on ten pediatric SARS-CoV-2 infection cases confirmed by real-time reverse transcription PCR assay of SARS-CoV-2 RNA. Symptoms in these cases were nonspecific and no children required respiratory support or intensive care. Chest X-rays lacked definite signs of pneumonia, a defining feature of the infection in adult cases. Notably, eight children persistently tested positive on rectal swabs even after nasopharyngeal testing was negative, raising the possibility of fecal-oral transmission.

SUBMITTER: Xu Y 

PROVIDER: S-EPMC7095102 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature