Respiratory tract infection-related healthcare utilisation in children with Down's syndrome.

ABSTRACT:

Purpose

Children with Down's syndrome (DS) are prone to respiratory tract infections (RTIs) due to anatomical variation, immune system immaturity and comorbidities. However, evidence on RTI-related healthcare utilisation, especially in primary care, is incomplete. In this retrospective cohort study, we use routinely collected primary and secondary care data to quantify RTI-related healthcare utilisation in children with DS and matched controls without DS.

Methods

Retrospective cohort study of 992 children with DS and 4874 matched controls attending English general practices and hospitals as identified in Clinical disease research using LInked Bespoke studies and Electronic health Records (CALIBER) from 1997 to 2010. Poisson regression was used to calculate consultation, hosp

SUBMITTER: Manikam L 

PROVIDER: S-EPMC7095390 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature